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The chemical potentially caused a decrease in saliva secretion after exposure. Advocates claimed CBD could help treat or reduce the effects of insomnia, joint pain, anxiety, Parkinson’s and Crohn’s disease, among other conditions. However, there is little evidence supporting the chemical’s positive effects. Cannabidiol (CBD) is a widely used marijuana ingredient in U.S. products. Manufacturers have been adding the chemical to cosmetic products, food, dietary supplements and medications for added health benefits.
A lab study carried out one month later concluded that CBD significantly reduced the extent of liver inflammation, oxidative/nitrative stress, cell death as well as having showed other protective effects. Yet another 2011 study reveals that cannabidiol causes the death of activated Hepatic Stellate Cells (HSCs) in liver fibrosis. Nash disease (Non-Alcoholic SteatoHepatitis) is a progressive form of Non-Alcoholic Fatty Liver Disease (NAFLD), which affects one in three Americans.
While excessive fat accumulation in the liver has previously been thought to be harmless, studies including ours, have demonstrated that NAFLD can progress to steatohepatitis, fibrosis, cirrhosis and even hepatocellular carcinoma . By 2020, it is estimated that progressive NAFLD would become the leading cause of advance liver disease requiring liver transplantation in patients . Since CU has been associated with reduced prevalence of both obesity and DM [7–9], we surmised that CU might also have modulatory effects on the prevalence of NAFLD. I’d assume if people are chosing to supplement their “medicines” with CBD Oil, its usually after long time use with Zero success, not to mention the multiple side effects these lab created medicines likely already produced in ones body.
This article serves purely as education and has not been evaluated by the FDA. PLEASE tell your doctor that you’re using CBD oil, especially if you’re on medications.
Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. Now that CBD oil is appearing in different products, anyone with liver damage needs to be alert to this. A doctor or specialist should be consulted before adding it to the diet. Note, the study cited in the article was very small with children under physician care but if you are a liver patient it is a cautionary note if you are considering CBD oil. We are not aware of any research that would suggest using it more broadly but consult your doctor.
While there are, at this point, few clinical research studies about the medical benefits of CBD oil for dogs, there is an abundance of anecdotal evidence of the therapeutic effects of CBD for pets. Although cannabis has been approved for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) and Dravet syndrome in patients 2 years and older, its use in other conditions, such liver disease, is an unknown field.
So yes, you may be jumping the gun by taking CBD to address a health issue when its use is not yet supported by clinical evidence that would pass muster with the FDA. But that clinical evidence won’t be available any time soon, and many people don’t want to wait a decade before finding out for themselves if CBD is effective for their needs. Mallat A, Lotersztajn S. Cannabinoid receptors as therapeutic targets in the management of liver diseases. Magen I, Avraham Y, Berry EM, Mechoulam R. Endocannabinoids in liver disease and hepatic encephalopathy.